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The GLP Truth

Drug Pipeline

Next-generation obesity medications in development: retatrutide, orforglipron, amycretin, CagriSema, and the science behind triple-agonist therapy.

Drug research
Phase 3

Retatrutide Phase 3 Data Expected by Year-End: The Triple Agonist That Could Change Everything

Eli Lilly's triple-receptor agonist (GIP + GLP-1 + glucagon) showed 24%+ weight loss in Phase 2—the highest of any obesity drug in history.

Pipeline Watch · 4 min read
FDA Approval

Orforglipron Approved: First Oral GLP-1 Changes the Game

Daily pill at $149/month eliminates injection anxiety for 30% of eligible patients who never started GLP-1 therapy.

April 2026 · 8 min read
Upcoming

Next-Gen Drugs in the Pipeline: Amycretin, CagriSema, Survodutide

Novo Nordisk's amylin combo showed 13% loss at just 12 weeks. The next generation of obesity medications is arriving fast.

Pipeline Analysis · 7 min read
Physician-Led Program · Lion MD
Oral GLP-1 Programs
Daily pill options now available. No injections required. Full physician protocol included.
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